Tuesday 22 April 2008

Drugs for the hell of it

Five emergencies – all went by ambulance.

If you have an anaphylactic friend who carries an Epipen or Anapen, don’t panic when they tell you they’ve eaten something nasty, like a peanut and they’re swelling up. If you use the injection device too quickly and without calm rehearsal, you’ll waste an opportunity to save their life if things become a little more complicated later on. If they just have a nasty rash and a bit of a puffy face, they’re not yet in danger.

The friends of a 30 year-old female who ‘fainted’ whilst having a reaction was injected twice; once by her friend, who failed to get it right and the adrenaline went to waste, and again by a stranger who happened to know what to do (well, she read the instructions) and managed to get the stuff into the patient’s muscle. The fact is, she didn’t really need either injection and it’s just as well only one of them took effect, as 0.6mg of adrenaline (small dose as it is) may have had the patient’s heart running a wee bit faster than it should while she was intoxicated.

Her BP was high, as expected, but it soon settled down again. She was convinced she was having a life-threatening reaction to something she ate and had instructed her mates to inject her. Neither of her friends was particularly confident about it and one of them repeatedly berated herself for getting caught out – hardly her fault and at least she tried to do the right thing.

Whether the lady in question actually had a reaction is debatable but the Epipen was an extreme measure, given her condition when I arrived – there was no life-threatening airway problem and very little evidence of swelling anywhere. Maybe she panicked.


Another allergic reaction and this time the 28 year-old man was convinced he’d eaten a peanut or a meal with peanut in it but again he looked fine – a little shaken up but alive. There was already an ambulance on scene and I popped my head inside to see if I was needed – I wasn’t, so I left to do my paperwork.

I wonder if there’s an element of panic-stress involved in people with sensitivities combined with alcohol. I’m not presuming that I know how they feel, of course, I just wonder if it’s worth further study. Maybe a moderate alcohol intake increases a person’s fear of allergic reaction or it creates the illusion of symptoms associated with it.


Into a West End casino for a 35 year-old female with chest pain next. She was Russian and couldn’t explain her known congenital heart defect clearly for me to understand what it was and how it could be connected to her recent experience of chest, sub-scapular and left arm pain. I didn’t want to take a chance and when the crew turned up and an ECG was carried out (confirming nothing in particular), I advised her to go to hospital.


A red call that should have been green – ‘chest pain’ had been given for someone with 'shoulder pain'. I queried it but got the usual stock answer; ‘that’s what the caller said’. This wasn’t exactly the case when I got on scene. The patient, who’d dislocated his shoulder while dancing (don’t ask) denied claiming that he had chest pain and the caller, one of his friends, denied it also.

He was a nice lad with gritted teeth (such was his pain) but his mates thought it was hilarious. Dislocations are very painful, especially at large joints, so I sympathised. He’d need morphine because the entonox wasn’t touching it.

Then another surprise when the crew showed up and it wasn’t the LAS. In fact I didn’t even recognise the uniform at first. The St. John Ambulance (SJA) were running on emergency calls tonight apparently – not that I knew anything about it, so it was a bit of a shock to realise that I wouldn’t be handing over to a crew I knew had the same training as me but instead I’d be handing over to three young people with basic ambulance aid knowledge (they told me). They were very nice people but unknown entities on a busy Friday night make me nervous and I’d much rather see one of my own crews arriving to help me out and take over the care of a patient – no offence to the SJA, of course.


The last call of the night, for example – this is when I need professional crews I know and trust. An unknown male was unconscious after taken GHB. The caller had given the wrong address several times and I crawled up and down the road given with the ambulance crew. It was ten minutes before the caller got some of his facts right and we were directed to the far end of the road we were on and it was only by accident that I was waved down by a delivery man who pointed to a window on the third floor of a building I wasn’t going to. A windmill was leaning out of it, so I let the crew know where I was heading and parked up.

The man met me at the gate and led me upstairs. The place reminded me of the grotty house that Steptoe and Son used to live in.

‘We were having sex and he had some kind of fit and then wet himself and fell down’, the man explained nonchalantly as he took me to the very top of the narrow staircase.

It was more than I wanted to know as I lurched into the darkness behind him. I could hear the crew arriving outside, so I wouldn’t be on my own with this guy for too long.

I was led into a dimly lit bedroom, cluttered with rubbish, and I could see no-one else. The man went to the side of the bed and pointed.

‘We’ve both had GHB but not a lot.’

I looked over and saw the patient for the first time. He was lying on his back, eyes glazed, mouth open and the very last breaths were coming out of him as he grunted into oblivion.

I went to his side and opened his airway. I got no response (and I wasn’t expecting any), so I continued with the most basic emergency care...airway and breathing. The crew arrived and I think they were just as taken aback by the sudden drama as the man who’d led me here.

‘Is he alright?’ he asked stupidly.

‘No, he’s not’, I replied sharply.

Although there was a paramedic on the crew, he wasn’t yet registered, so couldn’t carry out all of his skills or give many of his drugs unless supervised, so I was carrying the can alone on this one. I suggested that we move fast and get the patient to the ambulance but we had a problem with the carry chair; it had become damaged and wouldn’t support the patient’s weight safely, so we wre stuck there until a solution could be found.

We were now supporting the man’s breathing with a bag-valve-mask (BVM) and oxygen. An OP airway had gone in without a gag reflex and his pulse was slowing to a crawl. He would arrest soon if we didn’t do something to change the situation.

I looked at his pupils; they were pin-point. I had been told that he’d only taken GHB and cocaine but I was convinced he had taken much more than that.

‘Let’s give him narcan’, I suggested.

He was given 800mcg of the stuff IV and we waited for a response but got nothing. I had called control to request another ambulance and had made it clear that we couldn’t wait but wait we did...for another 30 minutes.

All the while, the man who’d brought me into this crazy situation was pacing about but not looking particularly worried. He’d only met this guy tonight. They’d had drugs to fuel their passion and then sex, during which he’d mistaken his new mate’s heavy, noisy breathing for excitement when, in fact, he’d been having a seizure. It was only when the man had lost bladder control and wet the bed that he’d realised something was amiss and had stopped. If I was in the same situation, I’d be worried sick.

I had broken open the first glass vial of narcan and it had cut my finger through my glove. Now blood was running over my finger underneath and I knew I was risking infection with this job. I decided to intubate the patient, there and then, rather than wait another eternity for the second crew I’d requested, so we moved him onto the bed and I got started but just as my laryngoscope blade left his mouth (I’d scoped the airway but it was too risky to try), his eyelids fluttered. Then the new crew entered the room.

Now we had enough hands to safely remove this patient. His condition changed as a Laryngeal Mask Airway (LMA) was put in his mouth – he began to gag and retch; this meant his level of consciousness was improving. It had taken 1.2mg of narcan but now he was further from danger than he was an hour before. We knew it wouldn’t last and it didn’t - he slumped back into unconsciousness as we carried him downstairs. He was given more narcan during the trip to hospital and taken straight into Resus where his life would be saved.

‘He’s got blood on him’, the doctor said in a worried tone.

‘Yeah, it’s mine’, I told him.

Be safe.

22 comments:

The Little Medic said...

Reason #2342 why drugs suck.

That must have been really scary to deal with! How could the other guy be so calm?

Anonymous said...

Thanks for that about Epipens - I've got one and I didn't know, and my GP remarked cheerfully as he signed the script, "They don't always work, you know" Oh. So when do I use it? It's for anaphalectic shock (wasps and certain medical drugs - prescription, not GBH!) Did the guy survive? I hope so.

Anonymous said...

Especially to non-life threatening transport SJA are used when the local ambulance service cant cope. They are very good (Usually), and it requires more than "Basic" ambulance-aid to crew an ambulance (ETA's are trained to just below technician level - no advanced stuff but they are pretty damn good, op airways, etc).

Anonymous said...

You certainly see life in the extremes! Love this post shows life as it really is for so many people. So glad its not mine.
Take care. Gill

BeckyG said...

I'm one of those people with a variety of weird and severe allergies that cause anaphylaxis. I have EpiPens that go everywhere with me (and a nebuliser as I'm also a severe, brittle asthmatic), and have had to use them on several occasions. Whilst I know that it can be dangerous to use too much adrenaline, my immunologist has always said to use my EpiPens if in any doubt at all. I wonder if your 'anaphylactic' patients today have also been given this advice. EpiPens aren't my first line of defence, of course - this is high dose anithistamines (2 different ones), which it is hoped will reduce the need to use the EpiPens. However, in these circumstances I often go on to need the adrenaline as the antihistamines can take too long to kick in. I wonder if your patients had taken antihistamines as a precaution (you will of course know this even though you don't mention it in your post), and if they had begun to work, thereby reducing swelling. Just a thought. The other thing is that yes, it is very frightening when you know you are allergic to something and then discover that you've accidentally been exposed to one of your allergens, so it can't be ruled out that there is a degree of panic, but then a sense of imminent death/foreboding is also a symptom of anaphylaxis. It's a difficult one to call, but surely it's better to follow the advice of an immunologist who says use the EpiPen if in doubt when it's something as potentially serious as anaphylaxis, that to sit and wait until it's too late.

Unknown said...

Hi XF,

Did you find out why the SJA were running on emergency calls? Was it due to short staffing, or because this call wasn't a particular emergency and the patient just needed transporting to hospital? Surely this could cause legal issues?

Also, I had always thought with dislocations that you could just "pop" them back into place? Was this patient taken to hospital just because it's a large joint and needs more care taking?

All the best,

Jason

Xf said...

fiz

GHB...easy mistake to make :-)

Don't hesitate to use your epipen if you are suffering a severe reaction...just don't get panicked into using it too quickly 'cos it's a once-only chance and will only be effective for a short while. You'd want that to be the few minutes you're waiting for an ambulance and not while the call is being made and you are just a little bit puffy.

Xf said...

anonymous

I agree that an ambulance can be crewed by individuals with a qualification that is less than EMT but not on frontline duties, surely?

Xf said...

beckyG

If you are indeed that sensitive, you should follow your code for survival...absolutely.

The woman in question was drunk and the combination of alcohol and a couple of shots of adrenaline could have had a potentially damaging effect on her system.

She was already 'wired' and seemed to have lots of concerns but she wasn't having an allergic reaction...not true anaphylaxis.

I'm concerned that Epipens are being given without much education in their contents and use.

Xf said...

jason

I wasn't told that SJA were covering with us and I should have been because I want to know who I'm working with. I had been given this as a red call for chest pain remember, so I'd need a bit more than transport if it went bad.

I don't want to be unkind to the crew or to SJA staff at all but I think my registration is at risk when I'm put in such circumstances without discussion or advice.

And NO, you don't just pop it back in. If he wanted to, he could but the pain can be excrutiating and reducing it can be damaging.

Anonymous said...

Most of the time sja are only used for transport, but if no ambos are available and a red call comes in who takes it? Tell them to hold on for 5 mins for the nearest crew to green up?

Surely an AED + Oxygen + Aspirin is better than no treatment at all...

Anonymous said...

Xf, thanks! I've always got away with using antihistmines, but I haven't been stung since I was seven but my leg swelled up so much I had to be cut out of the shorts I was wearing - wasps freak me out ( and aspirins and articial colourings!).

Anonymous said...

As an allergy sufferer and alcoholic, sorry, student I have been known to be just as bad at over-reacting while intoxicated - on the plus side I'm scared of needles and so refuse to use my Epipens unless absolutely necessary (as in someone else would have to use it for me!), so instead I just misuse NHS resources phoning for an ambulance whereas if I was sober I'd take a couple of antihistamines and if things were really bad a taxi to A&E.

SJA crews do ambulance support quite regularly round here - mostly GP urgents but if they're the closest resource or for backup they'll also cover red calls. As "anonymous" said, they're always two 'Emergency Transport Attendants' which is quite a high standard of training, and do an extra induction with EEAS before being signed off to work on behalf of the trust.

northern nurse said...

Epipens - The usual advice on prescription is to get them out and ready as soon as you know you've been exposed, and administer if any symptoms at all develop. My (limited) understanding of this is that if you wait until your airway is starting to obstruct or you get haemodynamic compromise then 1) It may be getting to a stage where you need the adrenaline IV anyway, and 2) You may no longer be in a position to self administer/direct others to administer. The absorption and half life of IM adrenaline is actually fairly long, and most sufferers have a second pen which they can use a few minutes later if required.

St John Ambulance - I know that they are used quite extensively oop north, they tend to be sent to ?Arrests if they can get there quicker than anybody else, as part of the general trend to community first responders, use of AEDs etc. Other than that, their main role is in PTS, intrahospital transfers of stable patients, or deployment at major events (e.g. sports fixtures, concerts etc.), the latter usually with the support of doctors, paramedics and nurses. My experience of them in A&E is that they are absolutely excellent, and as someone who was a member for quite a few years, I think they do a decent job. Having said that, I would have concerns about leaving the patient you described in their care - he'd had IV morphine, which as you know can cause a variety of problems which they couldn't reasonably be expected to cope with fully (non HCPs are no longer taught to distinguish cardiac/respiratory arrest as they'll hardly ever see a solo respiratory arrest, so your patient may well have ended up with unnescessary chest compressions,they'd also be unable to administer naloxone or intubate/LMA, and due to the fact that they never use morphine themselves may well have been unaware of what to look out for), and also they'd have been completely powerless if further parenteral analgaesia was required. In this position, I'd have travelled with them.

Jon Delaunt said...

SJA have a contract to provide support to the LAS. The crews volunteer as & when they so wish, shift times are open 24/7, and they kindly ask for a minimum committment of 5 hours. During the hours of 06:00 - 22:00, the crews book on with UOC and after 22:00 can work for EOC. Anyone working for EOC between 06:00 and 22:00 should be spoken to. They should generally only be sent to Greens & Ambers, but after 22:00, it really is open season and they can easily be sent on Red calls.

What I want to know is, why they were running three-up? Under the current legislation, three man crews are strongly contra-indicated, due to weight restrictions. If you'd like to get in touch with me, I'd be glad to discuss further.

Anonymous said...

Regarding your comment about SJA - they have thier place but I really don't feel they should attend emergency calls. Saying that, my (then) 9yr old daughter attended First Aid classes with the Red Cross when we lived in London and knew exactly what to do when she found her baby brother fitting in bed one night (febrile convulsion). She was amazingly calm, placing him into the recovery position, checking his airway and shouting on me. She got the phone and waited at the front door for the ambulance. I was very proud of her!

BeckyG said...

XF, I can fully understand your concern about EpiPens being handed out without proper instructions. Actually, when my GP first prescribed one for me (whilst waiting for my immunology referral to come through)he had to look up on the internet how to use it!

I see too how the combination of alcohol and adrenaline is not a good mix, and how it could be dangerous. I don't have that problem as I can drink very little alcohol because I'm on a cytotoxic med to treat my asthma (or rather, in the hope of treating it), so it's not something I'd considered before.

Out of interest, at what point would you call an allergic reaction 'anaphylactic'? Would it be only once the BP has dropped, or would it be at a particular level of oedema/swelling/DIB?

BeckyG said...

XF, I can fully understand your concern about EpiPens being handed out without proper instructions. Actually, when my GP first prescribed one for me (whilst waiting for my immunology referral to come through)he had to look up on the internet how to use it!

I see too how the combination of alcohol and adrenaline is not a good mix, and how it could be dangerous. I don't have that problem as I can drink very little alcohol because I'm on a cytotoxic med to treat my asthma (or rather, in the hope of treating it), so it's not something I'd considered before.

Out of interest, at what point would you call an allergic reaction 'anaphylactic'? Would it be only once the BP has dropped, or would it be at a particular level of oedema/swelling/DIB?

Xf said...

beckyg

As a matter of fact, you become and remain 'anaphylactic' when your body attempts to deal with what it perceives as a 'foreign invader' and remains on high alert for the next onslaught. You can stay anaphylactic (i.e. sensitive) for a long time and then, on your next exposure BAM! You've swollen up like a balloon and you can't breathe properly. It is potentially deadly, no mistake but it is NOT the same as having a rash on your arm.

When someone eventually does react like this, then they are having an anaphylactic reaction. Your are only anaphylactic if the reaction is progressively overwhelming; itchy rash, swollen lips and tongue, vomiting, swollen airway (this causes asphyxia and death), volume compromise leading to a drop in BP (this is why shock appears) etc., etc.

There is a LOT of stuff to explain about anaphylaxis but not in a single reply. Read up online; there's loads of research on it.

Xf said...

northern nurse

Yes....waiting for a swollen airway is probably not a good idea but my own experience of Adrenaline in this concentration is that it has a short half-life in fact, usually only minutes and is most effective when taken as a device for immediate anti-inflammation by vasoconstriction and the benefit of bronchoditation. Taking it too early may mean that its eficacy is decreased by the time you want it to really work and save your life and many people only carry one.

I agree with your statement however about those who would not be able to take it properly when they become worse but most never do anyway and rely on someone else to do it. Also, the number of actual anaphylactic people is lower than the number of people carrying epipens, just as I'd argue the number of actual serious asthmatics is lower than the number carrying (and using) ventolin but that's controversial talk, even though most agree. It upsets the pharmaceutical industry no end.

As with every patient I give meds to, or carry out any procedure that may have consequences, I DID go with them. I only stay behind if its an LAS crew with a paramedic on board and he/she has agreed to take over.

I'm a bit worried that you thought I'd give morphine and not be there for the handover at hospital. Surely you'd ask where I was yourself? The last thing I need is an angry nurse on my tail :-)

Anonymous said...

So it's not a good idea to 'pop' back in a dislocated shoulder al a Riggs in Lethal Weapon!?

Anonymous said...

As someone who has suffered several shoulder dislocations before I had the op to sort it out, I can tell you that it hurt me more than childbirth! I was knocked out(under medical supervision) each time they put it back in.

And the only way you can just"pop" it back in is if the joint is so badly damaged that is really loose. BUT with any relocation, you also run the risk of trapping the nerve, causing long-term damage and/or paralysis. So no, a Riggs is not a good idea!